Journal of Cancer Stem Cell Research

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Authorship Criteria

To be considered as an author, an individual must have played a role in the development of the project idea, the analysis of results and the writing of the manuscript. Authors must be willing to be held accountable for their results and procedures.

Experimental Subjects

Human Subject Research

All investigations relying on human participation MUST receive approval from the Institution Review Board (IRB) at the authors' institution or similar committee. Authors must be able to provide written evidence of such approval if needed. The Journal of Cancer Stem Cell Research maintains the right to reject research that does not meet the Journal's standards of ethical work. All human subjects must have given written consent to participate in the study, and have been given appropriate instructions during the trials. The authors must be able to provide the consent form if needed. Authors may be asked to submit a blank, sample copy of a subject consent form. In special circumstances if written approval was not given by subjects, the Journal of Cancer Stem Cell Research may accept work that was approved by the authors' ethics committee. It is imperative to conduct the studies in the most effective manner; protecting the subject's privacy and maintaining anonymity. Moreover, any information that can compromise patient privacy such as photos should not be included in the manuscript unless absolutely necessary. In such cases the subject must provide written complete Consent Form for Publication in Journal of Cancer Stem Cell Research (PDF). Complete information about patient privacy can be found in the International Committee of Medical Journal Editors (ICMJE) Privacy and Confidentiality guidelines.

Clinical Trial

Journal of Cancer Stem Cell Research follows the World Health Organization's (WHO) definition of a clinical trial:

Any research study that prospectively assigns human participants or groups of humans to one or more health-related interventions to evaluate the effects on health outcomes...Interventions include but are not restricted to drugs, cells and other biological products, surgical procedures, radiologic procedures, devices, behavioral treatments, process-of-care changes, preventive care, etc.

Clinical trials must adhere to the requirement and policies relating to human research. Moreover, clinical trials must be conducted according to the following guidelines, as outlined by the International Committee of Medical Journal Editors (ICMJE) Obligation to Register Clinical Trials:

  • Trials initiated after July 1, 2005 must be registered in a publicly accessible registry before patient recruitment has begun. We will not consider studies that have been registered retrospectively.
  • Trials initiated before July 1, 2005 must be registered before submission.

Animal Research

All research involving vertebrates or any other regulated invertebrates must receive approval by the authors' Institutional Animal Care and Use Committee (IACUC) or by the corresponding ethics committee(s). Before beginning of research, approval must have been received. Proof of approval and animal welfare consideration must be included with the submission. The Journal of Cancer Stem Cell Research maintains the right to reject research that does not meet the Journal's standards of ethical work regarding Animal Care. Where unregulated animals are used or ethics approval is not required by a specific committee, authors should highlight this fact and proceed to provide an explanation why ethical approval was not required. All exemptions from the relevant rules should be included in the submission. We strongly urge authors to adhere to the ARRIVE (Animal Research: Reporting of in Vivo Experiments) guidelines as a reference for all submissions relying on animal research. Manuscripts involving research on non-human primates must contain details about animal welfare, including information about housing, feeding, environmental enrichment and steps taken to minimize suffering (use of anesthesia and method of sacrifice if appropriate). These accounts must be line with the recommendations of the Weatherall report, The use of non-human primates in research.


Assay validation: All bioassay and potency estimates should be given with the precision of these estimates. For bioassay the main measures of precision are:

  • Standard deviation
  • Standard error of the mean
  • Coefficient of variation
  • 95% confidence limits

It is the responsibility of authors to provide data that have reproducible results and are not found due to random variables. Though no steadfast rules apply, researchers should strive to conduct at least three trials that display similar results. Appropriate statistical methods should be used to test the significance of differences observed in results.

Image Guidelines

  • Brightness, contrast, or color balance may be mainted for clarity of the image.
  • No specific feature within an image may be modified in any way, shape or form.
  • Grouping of images should be done in an effective clear manner, including appropriate dividing lines to allow the reader to understand the distinct images.


Pranela Rameshwar, Ph.D.
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Mariusz Ratajczak, M.D., Ph.D. ...
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Justin Lathia, Ph.D.
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